Squamous metaplasia

Squamous metaplasia refers to benign (non-cancerous) changes in the epithelial linings of certain organs within the body. These cells assume a more squamous morphology. Common sites for squamous metaplasia include the bladder and cervix. Smokers often exhibit squamous metaplasia in the linings of their airways. These changes don't signify a specific disease, but rather usually represent the body's response to stress or irritation. Vitamin A deficiency can lead to squamous metaplasia.

In regards to the cervix, squamous metaplasia can sometimes be found in the ectocervix, as it is composed of squamous epithelium, whereas the endocervix is composed of columnar epithelium[1]. Squamous metaplasia in the cervix are susceptible to dysplasia (precancerous changes), which is why a smear test can be performed to monitor changes.

  1. ^ Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; & Mitchell, Richard N. (2007) Robbins Basic Pathology (8th ed.). Saunders Elsevier. pp. 716-720 ISBN 978-1-4160-2973-1